Hyaluronan, also known as hyaluronic Acid or hyaluronate, is a substance called a glycosaminoglycan which is present within ovarian follicles, the fallopian tube and the uterus. Hyaluronan binds to its receptor, which is present on the lining of the uterus, hence the trade name Embryo Glue™.
It has been shown in several randomised controlled trials that hyaluronan improves pregnancy rates in some couples having an embryo transfer. The trials showing benefit of the addition of hyaluronan have all been in a media (nutrient solution in which embryos are grown) by Vitrolife. The mechanism by which the addition of hyaluronan works is uncertain.
Who is Embryo Glue™ best suited for?
Using hyaluronan has been shown to benefit couples who are aged over 35 years, those who have poor quality embryos and who have had three unsuccessful embryo transfers (failed implantation).
Are there any risks when using Embryo Glue™?
There is no information on birth defects after the use of Embryo Glue™ but several hundred live births have been reported after the use of hyaluronan in culture medium.
What is the cost?
The use of of Embryo Glue™ incurs extra cost. Please see our price range.